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Biotin is a high-affinity ligand for streptavidin and avidin proteins
NCC#CC1=C2C(=O)N(C3CCC(=O)NC3=O)C(=O)C2=CC=C1 Purity (HPLC) >= 95% Shipping Conditions Room temperature Storage Conditions Refrigerated Shelf Life 12 months after the date of delivery Regulatory Statement For Research Use Only
Product Name Azide-Lys(m-PEG4)-Val-Ala-PAB(m-PEG4) Synonyms CAS Number Related CAS Molecular Formula C41H70N8O14 Molecular Weight 899
43 SMILES: OC1=CC2=C(C=C1)C1(OC(=O)C3=CC=C(C=C13)C(=O)NCCCN=[N]#N)C1=CC=C(O)C=C1O2 Purity (HPLC): ≥ 95% Shipping Conditions: room temperature Storage Conditions: Refrigerated Regulatory Statement: For Research Use Only
Mal-Propionyl-Beta-Ala-Val-Ala-PAB(m-PEG8)-Exatecan fret Biotin is a high-affinity ligandSOLU KNEX cleavable linker features a Val Ala dipeptide. In this product, m PEG8 is attached to the commonly used self immolative para aminobenzyl (PAB) moiety to increase aqueous solubility. The payload is Exatecan, a highly potent topoisomerase I inhibitor derived from camptothecin, which induces DNA damage by stabilizing the topoisomerase IDNA complex, resulting in cell cycle arrest and apoptosis. Derived from established ADC linker architectures,
