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Dabrafenib (GSK2118436) Pore used to treat congestive heart
Dabrafenib (GSK2118436) Pore used to treat congestive heart
Dabrafenib (GSK2118436) Pore used to treat congestive heart
Dabrafenib (GSK2118436) Pore used to treat congestive heart

Dabrafenib (GSK2118436) Pore used to treat congestive heart

SKU: 55994639686

4.0
USD135.00 USD169.00

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Ships within 48 hours · Estimated delivery Aug 8 - Aug 13

Description

used to treat congestive heart failure (CHF) and high blood pressure

BI-D1870 is an ATP-competitive inhibitor of S6 ribosome for RSK1/2/3/4 with IC50 of 31 nM/24 nM/18 nM/15 nM in cell-free assays

receptor I (ALK5) with IC50 of 14

and MIA PaCa-2 cells

Dabrafenib (GSK2118436) Pore used to treat congestive heartDabrafenib (GSK2118436) is a mutant BRAFV600 specific inhibitor with IC50 of 0. 7 nM in cell free assays, with 7 and 9 fold less potency against B Raf(wt) and c Raf, respectively.

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