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Karlach, Fury of Avernus Starting off the top five today is Karlach, Fury of Avernus

Lets look at a deck built around this powerful card: "The Plague Urzas Saga Theme Deck" Creatures (16) 1 Blood Vassal 1 Flesh Reaver 1 Sanctum Guardian 1 Silent Attendant 3 Disciple of Grace 3 Unworthy Dead 3 Voice of Grace 3 Wall of Junk Spells (20) 2 Disenchant 2 Expunge 2 Humble 1 Befoul 1 Corrupt 1 Opal Acrolith 1 Pariah 1 Sicken 1 Worship 2 Rune of Protection: Black 4 Pestilence 2 Urza's Armor Lands (24) 12 Swamp 7 Plains 2 Polluted Mire 3 Drifting Meadow As you can see, this is basically one of the most powerful theme decks ever built

I was going to have the type line instead of the mana symbol, but the person wanted it to be more minimalist.

If destroyed, Fire Hand destroys a monster on your opponents side of the field in retaliation