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The primary aliphatic amine of the red-fluorescentSulforhodamine 101 cadaverine (Texas Red C)can be reversibly coupled to aldehydes and ketones to form a Schiff base - which can be reduced to a stable amine derivative by sodium borohydride (NaBH4) or sodium cyanoborohydride (NaCNH3) to form new biotinylated probes
By fusing eDHFR to a protein of interest and introducing TMP linked to a probe—such as a fluorescent dye
Product Name: 6-ROX alkyne Synonyms: 6-Carboxy-X-rhodamine alkyne CAS Number: N/A Molecular Formula: C36H33N3O4 Molecular Weight: 571
Product Name DOTA-tris(t-Bu)ester-PEG3-C2-azide Synonyms CAS Number n/a Related CAS Molecular Formula C36H68N8O10 Molecular Weight 772
CRBN5-SNAP2-0C-PIP Size:100nmol The primary aliphatic amine ofCRBN5 SNAP2 0C PIP is a SNAP PROteolysis TArgeting Chimera (SNAP PROTAC), which recruit the VHL or CRBN ubiquitin E3 ligases to induce the degradation of SNAP fusion proteins. Endogenous tagging enabled the visualization and the selective depletion of a SNAP clathrin light chain fusion protein using SNAP PROTACs. The addition of PROTACs to the SNAP tag reagent toolbox facilitates the comprehensive analysis of protein function with a single gene
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