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Mal-Propionyl-Dap(m-PEG4)-Val-Cit-PAB(m-PEG4)-Exatecan only Berishvili

SKU: 82012380188

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USD495.00 USD540.00

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Description

Berishvili

Product Name Thalidomide-5'-C3-OH Synonyms CAS Number 2357113-52-9 Related CAS Molecular Formula C16H16N2O5 Molecular Weight 316

Product Name Fmoc-Val-Ala-PAB(m-PEG8) Synonyms CAS Number Related CAS Molecular Formula C48H68N4O14 Molecular Weight 925

803 SMILES OC(=O)CN1CCN(CC(O)=O)CCN(CC(=O)NCCOCCOCCOCCOCCOCCOCC#C)CCN(CC(O)=O)CC1 Purity (HPLC) >= 95% Shipping Conditions Room temperature Storage Conditions Refrigerated Shelf Life 12 months after the date of delivery Regulatory Statement For Research Use Only

Mal-Propionyl-Dap(m-PEG4)-Val-Cit-PAB(m-PEG4)-Exatecan only BerishviliSOLU KNEX cleavable linker features a Val Cit dipeptide. In this product, a Mal Propionyl Dap(m PEG4) moiety replaces the conventional maleimidocaproyl (MC) unit to enhance aqueous solubility. The Mal Propionyl group may also improve retro Michael addition stability during antibody conjugation. Additionally, m PEG4 is attached to the commonly used self immolative para aminobenzyl (PAB) moiety to further increase aqueous solubility. The payload is

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