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Carmichael
638 Purity (HPLC) >= 95% Solubility DMSO
309 SMILES CC(C)(C)OC(=O)CCN1CCNCC1 Purity (HPLC) >= 95% Shipping Conditions Room temperature Storage Conditions Refrigerated Shelf Life 12 months after the date of delivery Regulatory Statement For Research Use Only
Structural basis for the action of the drug trametinib at KSR-bound MEK
DBCO-Dap(m-PEG4)-Val-Ala-PAB(m-PEG4)-PNP biochemical CarmichaelSOLU KNEX cleavable linker features a Val Ala dipeptide. In this product, a DBCO Dap(m PEG4) moiety replaces the conventional maleimidocaproyl (MC) unit to enhance aqueous solubility. DBCO is a strained alkyne commonly used in copper free click chemistry, specifically in the strain promoted azide alkyne cycloaddition (SPAAC) reaction. Additionally, m PEG4 is attached to the commonly used self immolative para aminobenzyl (PAB) moiety to further
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