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Mal-Propionyl-PEG4-Gly-Gly-Phe-Gly-PAB(m-PEG8) ether and broad absorption spectra

SKU: 73825514140

4.9
USD195.00 USD244.00

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Description

and broad absorption spectra

Product Name Mal-Lys(m-PEG4)-Gly-Gly-Phe-Gly-PAB Synonyms CAS Number Related CAS Molecular Formula C42H57N7O13 Molecular Weight 867

Product Name Mal-Acetyl-Dap(m-PEG4)-Val-Ala-PAB(m-PEG4)-PNP Synonyms CAS Number Related CAS Molecular Formula C51H73N9O20 Molecular Weight 1132

which readily reacts with an alkyne via click chemistry

Mal-Propionyl-PEG4-Gly-Gly-Phe-Gly-PAB(m-PEG8) ether and broad absorption spectraSOLU KNEX cleavable linker features a Gly Gly Phe Gly (GGFG) peptide. The conventional maleimidocaproyl (MC) unit is replaced by Mal Propionyl PEG4 moiety to enhance aqueous solubility. The Mal Propionyl group may also improve retro Michael addition stability during antibody conjugation. m PEG8 is attached to the commonly used self immolative para aminobenzyl (PAB) moiety to increase aqueous solubility. Derived from established ADC linker

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