CA-amide-PEG4-Biotin alkyne Molecular Glues for Targeted Protein

Molecular Glues for Targeted Protein Degradation: From Serendipity to Rational Discovery

322 SMILES OC(=O)CCCOC1=CC=C2C(=O)N(C3CCC(=O)NC3=O)C(=O)C2=C1 Purity (HPLC) >= 95% Shipping Conditions Room temperature Storage Conditions Refrigerated Shelf Life 12 months after the date of delivery Regulatory Statement For Research Use Only

also referred to as the Cu(I)

& Michalski

CA-amide-PEG4-Biotin alkyne Molecular Glues for Targeted ProteinHaloTag is a self labeling protein tag engineered from the haloalkane dehalogenase DhaA, originally isolated from Rhodococcus rhodochrous. Its active site binds chloroalkane (CA)substrates, forming an irreversible covalent bond. This stable linkage between the HaloTag protein and its ligand enables rapid and efficient isolation and purification of tagged proteins. CA amide PEG4 Biotin is a Biotin HaloTag ligand that enables rapid labeling of Halo