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Mal-Propionyl-PEG2-Gly-Gly-Phe-Gly-PAB(m-PEG8)-MMAE Size:10mg Product Name Inavolisib Synonyms GDC-0077

SKU: 72063362617

4.1
USD445.00 USD482.00

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Description

Product Name Inavolisib Synonyms GDC-0077 CAS Number 2060571-02-8 Related CAS Molecular Formula C18H19F2N5O4 Molecular Weight 407

Ceccarelli

no extreme temperatures or solvents are required

Product Name tert-butyl N-[(4-bromophenyl)methyl]-N-(methyl-d3)carbamate Synonyms tert-butyl N-[(4-bromophenyl)methyl]-N-(²H3)methylcarbamate CAS Number n/a Related CAS Molecular Formula C13H18BrNO2 Molecular Weight 303

Mal-Propionyl-PEG2-Gly-Gly-Phe-Gly-PAB(m-PEG8)-MMAE Size:10mg Product Name Inavolisib Synonyms GDC-0077SOLU KNEX cleavable linker features a Gly Gly Phe Gly (GGFG) peptide. The conventional maleimidocaproyl (MC) unit is replaced by Mal Propionyl PEG2 moiety to enhance aqueous solubility. The Mal Propionyl group may also improve retro Michael addition stability during antibody conjugation. m PEG8 is attached to the commonly used self immolative para aminobenzyl (PAB) moiety to increase aqueous solubility. The payload is monomethyl auristatin E (MMAE), a

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