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MC-Gly-Gly-Phe-Gly-PAB(m-PEG4) oregon green SOLU-KNEX® cleavable linker features a

SKU: 66897766293

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Description

SOLU-KNEX® cleavable linker features a Val-Ala dipeptide

Product Name Thalidomide-5'-O-PEG2-C2-azide Synonyms CAS Number 2640388-57-2 Related CAS Molecular Formula C19H21N5O7 Molecular Weight 431

Induced degradation of SNAP-fusion proteins

Fitzgibbons

MC-Gly-Gly-Phe-Gly-PAB(m-PEG4) oregon green SOLU-KNEX® cleavable linker features aSOLU KNEX cleavable linker features a Gly Gly Phe Gly (GGFG) peptide. In this product, m PEG4 is attached to the commonly used self immolative para aminobenzyl (PAB) moiety to increase aqueous solubility. Derived from established ADC linker architectures, SOLU KNEX ADC linkers integrate solubilizing moietiessuch as PEG, amine containing groups, or polysarcosine (PSAR), to enhance aqueous solubility. Solubility and physicochemical properties can be

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