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Fmoc-Val-Ala-PAB(m-PEG8)-PNP Size:10mg which are advantageous for consistent

SKU: 52083363054

4.8
USD345.00 USD388.00

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Description

which are advantageous for consistent signal detection

Linker substitution influences succinimide ring hydrolysis equilibrium impacting the stability of attachment to antibody-drug conjugates

Product Name DBCO-Dap(m-PEG4)-Val-Cit-PAB(m-PEG4)-MMAE Synonyms CAS Number Related CAS Molecular Formula C100H150N14O25 Molecular Weight 1948

Product Name DOTA-tris(t-Bu)ester-C3-propanamido-maleimide Synonyms CAS Number n/a Related CAS Molecular Formula C38H65N7O10 Molecular Weight 779

Fmoc-Val-Ala-PAB(m-PEG8)-PNP Size:10mg which are advantageous for consistentSOLU KNEX cleavable linker features a Val Ala dipeptide. In this product, m PEG8 is attached to the commonly used self immolative para aminobenzyl (PAB) moiety to increase aqueous solubility. Derived from established ADC linker architectures, SOLU KNEX ADC linkers integrate solubilizing moietiessuch as PEG, amine containing groups, or polysarcosine (PSAR), to enhance aqueous solubility. Solubility and physicochemical properties can be finely tuned

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