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Matyskiela
The Val–Cit dipeptide is optimized for cathepsin B cleavage in lysosomal environments
Product Name Lenalidomide-PEG1-C2-acid Synonyms Lenalidomide-4'-PEG1-C2-acid CAS Number 2225148-47-8 Related CAS Molecular Formula C18H21N3O6 Molecular Weight 375
Product Name Mal-Acetyl-Dap(m-PEG4)-Val-Cit-PAB(m-PEG8)-PNP Synonyms CAS Number Related CAS Molecular Formula C62H95N11O25 Molecular Weight 1394
Mal-Acetyl-Dap(m-PEG4)-Gly-Gly-Phe-Gly-PAB(m-PEG4)-MMAE Fluorescent MatyskielaSOLU KNEX cleavable linker features a Gly Gly Phe Gly (GGFG) peptide. In this product, a Mal Acetyl Dap(m PEG4) moiety replaces the conventional maleimidocaproyl (MC) unit to enhance aqueous solubility. The Mal Acetyl group may also improve retro Michael addition stability during antibody conjugation. Additionally, m PEG4 is attached to the commonly used self immolative para aminobenzyl (PAB) moiety to further increase aqueous solubility. The payload
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