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MC-Val-Cit-PAB(m-PEG8)-Exatecan cp 295 Purity (HPLC) >= 95%

SKU: 39906041668

4.2
USD495.00 USD529.00

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Description

295 Purity (HPLC) >= 95% Solubility DMSO

Product Name Lenalidomide-acetamido-O-PEG2-C2-Cl Synonyms Lenalidomide-4'-acetamido-O-PEG2-C2-Cl CAS Number n/a Related CAS Molecular Formula C21H26ClN3O7 Molecular Weight 467

Product Name 1-(methyl-d3)-2

Product Name Pomalidomide-5'-C4-amine HCl Synonyms CAS Number n/a Related CAS 1957236-35-9 (free base) Molecular Formula C17H21ClN4O4 Molecular Weight 380

MC-Val-Cit-PAB(m-PEG8)-Exatecan cp 295 Purity (HPLC) >= 95%SOLU KNEX cleavable linker features a Val Cit dipeptide. In this product, m PEG8 is attached to the commonly used self immolative para aminobenzyl (PAB) moiety to increase aqueous solubility. The payload is Exatecan, a highly potent topoisomerase I inhibitor derived from camptothecin, which induces DNA damage by stabilizing the topoisomerase IDNA complex, resulting in cell cycle arrest and apoptosis. Derived from established ADC linker architectures,

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