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which recruit the VHL or CRBN-ubiquitin E3 ligases to induce the degradation of SNAP-fusion proteins
Isoindole-
Product Name: Texas Red alkyne Synonyms: Sulforhodamine 101 alkyne CAS Number: N/A Molecular Formula: C68H66N6O12S4 Molecular Weight: 643
a Azide-Dap(m-PEG4) moiety replaces the conventional maleimidocaproyl (MC) unit to enhance aqueous solubility
CP-CPY pab-mpeg which recruit the VHL orSNAP tag is a self labeling protein derived from human O6 alkylguanine DNA alkyltransferase. At 20 kDa, SNAP tag is smaller than HaloTag (33 kDa), potentially reducing interference with the tagged proteins function. SNAP tag reacts with covalently with benzylguanine (BG)or chloropyrimidine (CP) derivatives, forming a stable thioether bonds that ensures durability for long term experiments or harsh conditions. SNAP tag can be used alongside other tags
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