Mal-Lys(m-PEG4)-Val-Cit-PAB(m-PEG4)-MMAE mal-propionyl-dap-m-PEG4 Product Name Phthalimidinoglutarimide-C3-O-PEG2-OH Synonyms Phthalimidinoglutarimide-4'-C3-O-PEG2-OH

Product Name Phthalimidinoglutarimide-C3-O-PEG2-OH Synonyms Phthalimidinoglutarimide-4'-C3-O-PEG2-OH CAS Number n/a Related CAS Molecular Formula C20H26N2O6 Molecular Weight 390

NCCOCC#CC1=C2C(=O)N(C3CCC(=O)NC3=O)C(=O)C2=CC=C1 Purity (HPLC) >= 95% Shipping Conditions Room temperature Storage Conditions Refrigerated Shelf Life 12 months after the date of delivery Regulatory Statement For Research Use Only

thus has excellent cell permeability

HaloTag is a self-labeling protein derived from the haloalkane dehalogenase DhaA from Rhodococcus rhodochrous

Mal-Lys(m-PEG4)-Val-Cit-PAB(m-PEG4)-MMAE mal-propionyl-dap-m-PEG4 Product Name Phthalimidinoglutarimide-C3-O-PEG2-OH Synonyms Phthalimidinoglutarimide-4'-C3-O-PEG2-OHSOLU KNEX cleavable linker features a Val Cit dipeptide. In this product, a Mal Lys(m PEG4) moiety replaces the conventional maleimidocaproyl (MC) unit to enhance aqueous solubility. Additionally, m PEG4 is attached to the commonly used self immolative para aminobenzyl (PAB) moiety to further increase aqueous solubility. The payload is monomethyl auristatin E (MMAE), a highly potent antimitotic agent that inhibits tubulin polymerization, leading to