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Mal-Propionyl-PEG6-Gly-Gly-Phe-Gly-PAB(m-PEG4) mmae 076 Purity (HPLC) >= 95%

SKU: 12914069975

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Description

076 Purity (HPLC) >= 95% Solubility DMSO

164 Purity (HPLC) >= 95% Solubility DMSO

DOTA bifucational chelator containing an amine group

which readily reacts with an alkyne via click chemistry

Mal-Propionyl-PEG6-Gly-Gly-Phe-Gly-PAB(m-PEG4) mmae 076 Purity (HPLC) >= 95%SOLU KNEX cleavable linker features a Gly Gly Phe Gly (GGFG) peptide. The conventional maleimidocaproyl (MC) unit is replaced by Mal Propionyl PEG6 moiety to enhance aqueous solubility. The Mal Propionyl group may also improve retro Michael addition stability during antibody conjugation. m PEG4 is attached to the commonly used self immolative para aminobenzyl (PAB) moiety to increase aqueous solubility. Derived from established ADC linker

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